Background: 

This study examined the personality characteristics of 40 schizophrenic inpatients of Psychiatry department, Susheela Tiwari Forest Medical Collage, Haldwani, Uttrakhand and 40 normal controls (General Health Questionnaire-12 negative) from Awas Vikas Colony, Rudrapur, Uttrakhand, India. Subjects fulfilling inclusion/exclusion criteria and giving written informed consent were included in the study. A comparison of their personality profile on Dimension Personality Inventory (DPI)-B revealed that there was significant difference (p<0.05) in the mean scores on different dimensions of personality between schizophrenic and normal group. Schizophrenics were found to be passive, non-enthusiastic, submissive, suspicious, depressive and emotionally instable however, normal individuals were on opposite dimension of these. Males were found to be assertive of both the groups. Study findings revealed that schizophrenics can be differentiated from normals on the basis of personality characteristics. 

In this paper, the Textural properties of normal and tuberculosis posterior and anterior chest radiograph were looked in this investigation. Where the patients especially from rural and remote areas in which there were not having facilities like well-equipped medical centers for blood test, sputum test and skin test, not even radiologist for reading radiologic findings. Here, we first extract the lung field by an interactive lung field segmentation based on active contour models well known called as snake model. After segmentation we analyze the pixel data within region of interest by using a first order statistical approach to extract the textural properties in classifying image as TB and Non TB. For both normal and tuberculosis radiographs, the grey scale intensity distribution within the region of interest was analyzed to study their respective characteristics. Statistically the tuberculosis infected radiographs manifested higher entropy and a lower mean value in their intensity distribution as compared to their normal peers.

Aim: 

The present study “Comparision of lignocaine 5% (hyperbaric) alone and lignocaine 5% (hyperbaric) with neostigmine for spinal anaesthesia” was conducted in 100 female patients (ASA I & II) in age group of 20-50 years of average built (46-64 kgs) undergoing various elective gynaecological surgeries. They were randomly divided into two groups. Group I consisting of 50 patients were given only lignocaine 5% (hyperharic) 2 cc with 1 cc Dextrose 5% and group II were given lignocaine 5% (hyperbaric) 2 cc with 100 µg of neostrigmine in 1 cc of 5% Dextrose, after subarchnoid block onset of block, duration of block, side effects, heart rate & mean arterial pressure were observed at different time points. Onset was early in groupII (Lignocaine with Neostigmine) 78.80 sec. than groupI (Lignocaine alone) 97.60 seconds. Duration of analgesia & motor block was prolong in groupII1 (Lignocaine with Neostigmine) (180 min. each) than group I (Lignocaine alone) (90 min. each). High incidence of nausea and vomiting observed in groupII1 (Lignocaine with Neostigmine) (64% & 48% respectively) than group I (Lignocaine alone) (20% & 8% respectively). Both groups are haemodynamically stable. 

Hypertension in pregnancy is a leading cause of both maternal and fetal mortality and morbidity.  Endothelial dysfunction and oxidative stress play a key role in the etiopathogenesis of preeclampsia. Recently hemeoxygenase-1 enzyme has been implicated as a contributing factor to the antioxidant capabilities in several organ systems. The objective of this study to evaluate hemeoxygenase-1 product, bilirubin levels in preeclamptic women. Thirty normal pregnant women attending the antenatal clinic and thirty preeclamptic women were recruited from Obstetrics and Gynecology Department, Narayana General Hospital, Nellore. Serum bilirubin levels were significantly elevated in preeclamptic women when compared with that of normal pregnant women (pvalue< 0.000).  This suggests that induction of hemeoxygenase-1 or its metabolites may be a promising therapeutic approach in the treatment of preeclampsia. 

Diabetes mellitus is one of the main threats to human health in 21st century. Diabetes is a heterogenous group of metabolic disorder due to defect in insulin secretion or action or both.CAD in diabetes carries a worse prognosis than in nondiabetic subjects. 

Background: 

Serum γ- glutamyl transpeptidase  is  a well  known  marker  for  alcoholic hepatitis. Recent studies suggests   possible association of γ- Glutamyl transpeptidase with metabolic syndrome. Obesity is an important risk factor for many cardio metabolic diseases like hypertension, diabetes mellitus, cardiovascular disease etc. Our study was conducted to assess    association of serum γ- glutamyl transpeptidase with body mass index and waist hip ratio which measure obesity. Materials and methods: 50  subjects with metabolic syndrome  and 50 age and sex matched healthy controls  both male and female  between 25-70 years of age  were recruited from General Medicine  department  of Narayana  Medical college and Hospital, Nellore, A.P. Serum  γglutamyl  transpeptidase was   measured by calorimetric  kinetic assay. Height, weight, waist circumference and waist-hip ratio are measured by standard anthropometric procedures.  BMI is calculated using the formula weight (kg) / height (m)2.  Systolic and diastolic blood pressures were recorded manually using mercury sphygmomanometer. Plasma glucose is analyzed by glucose oxidase method by automated chemistry analyzer.  Results: GGT is significantly elevated in subjects with metabolic syndrome (mean±SD 70.32 ± 23.97) IU/L compared to controls (mean±SD 25.30 ± 6.82) IU/L (P value <0.001). GGT is significantly correlated with BMI (r= 0.26 p<0.001) and waist hip ratio (r= 0.69 p<0.001).  Conclusion : Our  findings  suggest that elevated GGT  levels are elevated in subjects with metabolic syndrome  may contribute to their  susceptibility to cardiometabolic diseases  and  provide an additional evidence of  novel role of  GGT in metabolic syndrome risk evaluation. 

Background: 

Large quantities of fish are discarded at sea because it is uneconomic to preserve and bring them ashore .To find the utilization of the presently wasted by catch, an attempt has been made in the study to prepare Texturised dried fish granules, using minced fish meat and low- cost technology. The present research work was carried out on dried fish granules prepared from meat of Lizard fish (Saurida tumbil). Lizard fish granules were prepared with Standardized ingredients composition containing 10 g. salt, 2 g. Starch and 0.3 g. turmeric powder in 100 g. of fish meat. Final developed dried fish Granules had moisture content 5.7 %, 64.7 % Protein, 6.2 % Fat and Ash 1.2 % on the dry basis. Dried fish granules were packed in HDPE pouches and stored at room temperature. During the storage time product was Subject to organoleptic evaluation, assessment of biochemical parameters such as TMA, TVB-N, PV, FFA, Salt, Moisture and microbiological parameters such as TPC. Based on the organoleptic characteristics, Microbiological and Biochemical parameters it was concluded that dried fish granules were acceptable up to 3 month stored at room temperature. The developed Texturised fish granules from boiled fish minced meat imparted good odour and texture to the fish granules. Boiling reduces the bacterial count considerably and denatures the protein. Use of 10 g salt/100 g of minced fish meat further denatures the protein, release of some moisture. Drying for 12 hours at 43-45⁰C reduce the moisture. Due to low moisture level and high salt concentration, the product was stable up to 3 months. Well- dried fish granules have shelf life of several months and does not need any expensive facilities compared to frozen fish. If the raw materials used are quite fresh, the quality of the dried fish granules will also be very good. When decay fish are used, the texture of the dried fish granule is quite soft and disintegrates when boiled in water. 

Crab shell waste is excellent sources of chitosan (41-53%). Procedures for isolation of chitosan have been developed, along with investigation of its distinctive physicochemical properties. Optimal conditions for deproteinization of crab shell waste were 3.5% NaOH at 65 ⁰c for 2 hrs with solids to solvent ratio of 1:10(w/v). Optimal demineralization involved treatment with 1 N HCL at ambient temperature for 30 min with a solid solvent ratio of 1:15 (w/v). Removal of the carotenoid astaxanthin from the shell matrix required extraction with acetone before bleaching with 0.315% sodium hypochlorite solution for 5 min with a solid to solvent ratio of 1: 10(w/v).Chitin deacetylation was carried out at 15 psi/121 ⁰C using 50% sodium hydroxide solution for 15 min. After this step, samples were filtered off, washed with distilled water to neutral pH and dried in an oven at 60 ⁰C for 24 hrs. These studies demonstrated that process modification of crab production affected different characterization