Urinary tract infection is the most common infection which requires medical attention worldwide. Escherichia coli being the most common etiological agent for the infection and females are more susceptible to males. The uncontrolled use of antibiotics in UTI without AST has led to an increase in drug resistance. The effect of raising resistance, treatment is again going to the older drugs which were once discontinued due to availability of newer antibiotics. This study focused on the impact of sensitivity patterns in uropathogenic bacteria for fosfomycin and nitrofurantoin respectively. This study was a retrospective study for a period of one year in the department of Microbiology, Dr. R.P. Govt. Medical College Tanda at Kangra. High susceptibility was noted for the older drugs taken in the study which concluded that Nitrofurantoin and Fosfomycin proves to be a useful treatment option for community-based treatment of patients with resistant organisms.

Paederia foetida, Family Rubiaceae is an herbaceous climber medicinal plant, usually found in Himalaya region and also Bengal, Assam, Orissa and Bihar. It is known as “Prasarini” in local language Hindi. The present study deals with the pharmacognostic study and biochemical investigation of Prasarini stem. Stem powder was analyzed by using various parameters like macro & microscopic study, physicochemical tests (LOD at 105OC, alcohol soluble extractive value, water soluble extractive, total ash value and acid in soluble ash value), qualitative phytochemical analysis and development of HPTLC fingerprints profile.