In this study, it has been aimed to determine the fatty acid composition and ω-3/ω-6 ratios of the muscle tissue of rainbow trout (Oncorhynchus mykiss) fed and starved during 28 days. There

were no qualitative differences in the fatty acid composition of the muscle of the fed and starved fish. However, it was determined that there were increases in the amounts of total ω-6 and ω-3 polyunsaturated fatty acids (PUFAs) of fed fish, while found decrease in total saturated fatty acids (SFAs). There were increases in the levels of C18:1 ω-9, C18:2 ω-6, C18:3 ω-3 and C22:6 ω-3 in fed fish. The ω-3/ω-6 ratios of the muscle tissue of starved and fed fish were found to be 1.27 and 1.49, respectively. From these results, during 28 days starvation period, it can be said

that the fish can keep their saturated (SFA) and monounsaturated fatty acid (MUFA) metabolism although they showed a loss of weight. In conclusion, dietary ɷ-3 and ɷ-6 series fatty acids improved the muscle tissue quality of Oncorhynchus mykiss.

Introduction: Survival time data measure the time to a certain event, such as failure, death etc. These times are subject to be random variables. These data have the property for nonnegativeless and must have skewed distribution. The exponentiated exponential distribution can define as a generalization of the standard exponential distribution. It is obtained with Fisher information matrix under Type-II censoring for this distribution. 

Case Report: The aim of this study is to investigate estimating of parameters in exponentiated exponential distribution based on progressively censored survival time data. Moreover likelihood based confidence intervals are also investigated in the same data frame. It is also illustrate the results using bile duct cancer data set. 

Discussion: In this study we consider parameter(s) estimation in the EE distribution based on progressively censored samples. We also consider likelihood based confidence interval of the parameters in that distribution. We present a real data example where it is observed that the EE has a better fit compare to standard exponential, gamma, log-logistic, log-normal and Weibull.

Branded drug products are normally expensive than the locally marketed drug products of regional pharmaceutical companies. Generic substitution is very common in under-developed and developing countries including Bangladesh. The aim of the present study was to evaluate and compare dissolution pattern of locally branded drug products of Ranitidine HCl available in Bangladesh with the innovator brand of Ranitidine HCl (Zantac) marketed by GSK pharmaceutical company. Tablets of six brands of Ranitidine available in Bangladesh as well as Zantac were collected from a reputed pharmacy store in Dhaka, Bangladesh. Six tablets from each of the brands were used for the in-vitro dissolution study. Cumulative drug release was measured up to 50 minutes for all the brands. All the brands were compared with the innovator brand. Differential factor, f1 and similarity factor, f2 were determined. No significant difference was observed during in-vitro drug release pattern of brand A, B, D and F with the innovator brand, whereas brand C and E were significantly different from Zantac  . The drug release pattern is not an indicator of drug efficacy in the body. Nevertheless, it is a need to compare drug release pattern of generic brand with the innovator brand. Manufacturer of brand C and E are advised to revise their drug release pattern to be more similar with Zantac.

Pain management remains a vital concern in dental care and patient management. Complementary and Alternative Medicine (CAM) is considered as a mode of non- traditional medicinal therapy as opposed to conventional procedures based on Western medicine. Conventional therapy comprises allopathic treatment and practice by medical/dental practitioners and other professionals in the health sector. Allopathy involves the use of antagonists to combat disease/pathology/abnormal conditions. There has been a sharp rise in popularity of CAM interventions over the past few years due to dissatisfaction with conventional allopathic medicine, increased patient awareness and integration in medical decision making.

Physical properties of paddy are necessary for the design of equipment to handle, transport, process and store of the crop. These properties are evaluated as a function of moisture content of grain. In this study, some physical properties of raw paddy are discussed briefly. The grain was tested for bulk density, sphericity, thousand grain weight, size, angle of repose etc were determined with variable materials at 12 % moisture content wet basis. The total 25 varieties of paddy grown in the Konkan region were studied. The mean length, breadth, thickness, size, surface area, sphericity, thousand grain weight, angle of repose and bulk density of eight fine variety was found as 8.09 mm, 2.07 mm, 1.70 mm, 3.04 mm, 36.15 mm 2 , 0.37, 14.28 g, 28.23 and 543.5 kg/m3  respectively. The ten medium varieties of paddy were studied and found the mean length, breadth, thickness, size, surface area, sphericity, thousand grain weight, angle of repose and bulk density as 9.11 mm, 2.46 mm, 2.02 mm, 3.56 mm, 48.25 mm, 0.39, 22.77 g, 29.82 0  and 562.9 kg/m3  respectively. Also eight coarse varieties were studied and found the mean length, breadth, thickness, size, surface area, sphericity, thousand grain weight, angle of repose and bulk density as 8.95 mm, 2.77 mm, 2.04 mm, 3.70 mm, 50.98 mm, 0.41, 26.02 g, 29.940  and 600.5 kg/m3

 respectively.

Infections are one of the most common and fatal complications following trauma and complicate the recovery of a significant number of injured patients. Traumatised patients with infections

have a 5-fold higher mortality compared to those without infection.

Aim: This study was conducted with the aim to (1) Study the prevalence of pathogens in wounds due to trauma. (2) Analyze pathogen distribution according to wound type and site and (3) Determine the pattern of drug resistance. 

Methods: The study included a total of 100 patients admitted to Orthopedics, General surgery and Neurosurgery departments of NRI General Hospital within 24 hrs of trauma over a period of seven months. After initial step of wound management, samples collected were subjected to both aerobic and anaerobic culture method’s for identification of organisms and anti -microbial susceptibility testing was done.

Results: Of the hundred patients participated, majority were men [79%] and the average age of the patients was 46.8 yrs. The most common cause of trauma was Road Traffic Accidents [RTA](78%) ,followed by fall from height (6%), Occupational hazards (4%), Burns (2%) and other miscellaneous causes accounting for 10%.Lower extremities received highest number of wounds(52%) and have shown high rate of culture positivity. Of the wounds evaluated for culture (100), 28% were sterile and 72% were culture positive. Cultures have shown predominance of Gram negative bacilli (66.66%) than Gram positive bacteria (33.33%). Pseudomonas aeruginosa (P.aeruginosa) was the commonest organism (41.66%) followed by Staphylococcus aureus (S.aureus) (29.16%). Other organisms isolated belonging to different genera were of minor percentage. All the infections were monomicrobial except one. Distribution of pathogens according to wound site were more or less the same, the frequency of isolation of organisms was high in case of RTA and high rate of culture positivity was seen in Burns and occupational cases. Disinfection with commercial antiseptics soon after trauma prevented infection in case of minor trauma than major. Gram negative bacilli were sensitive to gentamicin, ofloxacin and ceftazidime; resistant to ciprofloxacin. Gram positive organisms were sensitive to gentamicin and ofloxacin; resistant to piperacillin and penicillin.

This theoretical perspective based writing denotes the magnitude of quality interactions between caregivers and their children. Attachment theory and mediated learning experience (MLE) theory

are two decisive foundations in order to rationalize this article. Firstly, the author describes the basic concepts of both theories. Afterward, the constructive discussion of theories is highlighted through critical comparison. There is no doubt about the contribution of attachment theory in terms of understanding the caregivers-children‟s responsive interaction that enhances their relationship quality and psycho-social aspects of children‟s development. In the same way, the theory of MLE is focused on its humanistic way of interaction process through which stimuli, mediator, and mediatee are connected in flexible, adaptive, and diversify manner. Moreover, the universal interaction criteria are essential for successful MLE as well. To connect with the topic of this article, both theories have implications in order to understand relationship and development at home, school, and daycare center that enrich the practice of inclusive and special needs education by using various innovation models.